Can Mutated Genes Cause Missing Teeth?

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Can Mutated Genes Cause Missing Teeth?

Missing teeth can pose many problems in life. Holes in the mouth make it harder to eat, more difficult to speak clearly, and even cause people to have lower self-confidence in their smiles. Luckily there are options that can fix missing teeth, including long-term and even permanent fixes like dental implants. 

A patient may only need one dental implant or multiple. Either way, once a dental implant has been placed and healed, care for these dental prosthetics is not unlike the oral healthcare routine for regular teeth. Every day, your teeth, including your dental implants should be brushed, flossing is imperative, mouth wash is important, and so are regular visits to your local San Diego dentist for professional cleanings and examinations. And, the better you take care of your dental implants, the longer they will last.

Dr. McBride is a San Diego dental implant specialist who can evaluate your dental health situation and provide you with options to remedy any problems that exist. This includes missing teeth.

Genes and Missing Teeth

Can Mutated Genes Cause Missing TeethThere are many ways that a person can suffer from missing teeth. Sports activities or violent attacks can lead to an impact on the mouth knocking teeth out. Car accidents can smash teeth. Poor oral hygiene can lead teeth to rot which can cause them to fall out. Improper bite and tooth grinding can cause teeth to chip, crack, and break. Genes too may contribute to missing teeth.

According to the National Institute of Dental and Craniofacial Research, as high as 20% of Americans can not develop their complete set of teeth. It is unclear why some people cannot develop a full set of chompers when they are born and as they grow, but research looking into this phenomenon has discovered that the PAX9 gene may be the culprit. For one family in Texas that did not have their first and second molars, it was a nutation of this gene that was shared in common.

In animal studies, when the PAX9 gene is removed, missing teeth are among the many defects that are noticed. In mice, the PAX9 gene is not inherited from either parent. By contrast, those in the Texas family that had a link of missing teeth to PAX9 gene mutations had only one of these genes that was mutated and the other was normal.

The researchers still have more work to do with respect to the impact of PAX9 gene mutations and missing teeth. It could be that each type of tooth in our mouth has its own unique genetic code that is what will determine the formation of a tooth or not.

Speak to a San Diego Implant Dentist Today

Missing teeth are not ideal and whether they happened at an older age in life from a life event or they never developed because of genetics, the good news is there are ways to address the condition. To learn more, please connect with the San Marcos cosmetic dentist at McBride Dental by calling (760) 471-100 to schedule a free consultation or professional cleaning and examination.

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